布羅福韋酯(CMX001) 是一種具有口服活性的Cidofovir (CDV) 親脂形式，對(duì)某些皰疹病毒，腺病毒和正痘病毒，比CDV具有更強(qiáng)的體內(nèi)外活性。 是一種用于治療巨細(xì)胞病毒、腺病毒、天花和埃博拉病毒感染的實(shí)驗(yàn)性抗病毒藥物。布羅福韋酯是西多福韋的前藥。與脂質(zhì)結(jié)合，該化合物被設(shè)計(jì)為在細(xì)胞內(nèi)釋放西多福韋，允許更高的細(xì)胞內(nèi)濃度和更低的血漿濃度西多福韋，有效提高其對(duì)dsDNA病毒的活性以及口服生物利用度。
3-(Hexadecyloxy)propan-1-ol
N,N'-Dicyclohexylmorpholine-4-carboximidamide
(Diethoxyphosphoryl)methyl 4-methylbenzenesulfonate
6-Aminopyrimidin-2(1H)-one
(S)-(((1-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid
3-(Hexadecyloxy)propyl hydrogen ((((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonate
((3-(Hexadecyloxy)propoxy)(hydroxy)phosphoryl)methyl 4-methylbenzenesulfonate
(S)-1-(2-Hydroxy-3-(trityloxy)propyl)-4-(((4-methoxyphenyl)diphenylmethyl)amino)pyrimidin-2(1H)-one
