卡博特韋是一種有效的HIV整合酶抑制劑, 用于治療和預(yù)防艾滋病毒感染, Cabotegravir抑制OAT1 (IC50為0.81 μM) 和OAT3 (IC50為0.41 μM)。
(R)-2-Aminopropan-1-ol
2,2-Dimethoxyethanamine
1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
(2,4-Difluorophenyl)methanamine
Methyl 4-methoxy-3-oxobutanoate
3-Hydroxy-2-methyl-4-pyrone
3-(Benzyloxy)-5-bromo-2-methylpyridin-4-ol
Dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
Methyl 5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2-carboxylate
3-(Benzyloxy)-2-methylpyridin-4(1H)-one
3-(Benzyloxy)-2-methyl-4H-pyran-4-one
Methyl (Z)-2-((dimethylamino)methylenE)-4-methoxy-3-oxobutanoate
Methyl 2-(((2,2-dimethoxyethyl)amino)methylene)-4-methoxy-3-oxobutanoate
