噠嗪是一種雜環(huán)芳香化合物，噠嗪作為苯環(huán)的生物電子等排體，其兩個(gè)氮原子能夠與靶蛋白形成氫鍵。在藥物研發(fā)中，噠嗪也經(jīng)常被用作吡啶、嘧啶和吡嗪的生物電子等排體。噠嗪衍生物已被鑒定為具有高選擇性和低毒性的潛在抗癌劑。
3,6-Dibromopyridazine
3,6-二溴噠嗪
3-Chloropyridazine
3-氯噠嗪
6-Chloropyridazine-3-carbonitrile
6-氯-3-噠嗪甲腈
Pyridazine-3-carboxylic acid
3-羧基噠嗪
3-Aminopyridazine
噠嗪-3-胺
Methyl 3-methoxypyridazine-4-carboxylate
3-甲氧基噠嗪-4-羧酸甲酯
4-(Chloromethyl)-3-methoxypyridazine hydrochloride
(3,6-Dichloropyridazin-4-yl)methanamine
3-Bromo-6-chloro-4-methylpyridazine
3-溴-6-氯-4-甲基噠嗪
Methyl 6-methoxypyridazine-3-carboxylate
6-甲氧基噠嗪-3-羧酸甲酯
6-Ethoxypyridazine-3-carboxylic acid
6-乙氧基噠嗪-3-羧酸
6-Aminopyridazine-4-carboxylic acid
6-氨基噠嗪-4-羧酸
6-(1H-Imidazol-1-yl)pyridazine-3-carboxylic acid
6-(1H-咪唑-1-基)噠嗪-3-羧酸
6-(Difluoromethyl)pyridazin-3-amine
4-Methyl-N-(2-morpholinoethyl)-6-phenylpyridazin-3-amine
4-甲基-N-(2-嗎啉乙基)-6-苯基噠嗪-3-胺
4,6-Dichloropyridazine-3-carboxylic acid
4,6-二氯噠嗪-3-羧酸
3-Bromo-6-(trifluoromethyl)pyridazine
3-溴-6-(三氟甲基)噠嗪
3-Chloro-4-(trifluoromethyl)pyridazine
3-氯-4-(三氟甲基)噠嗪
2-Ethoxypyrazine
2-乙氧基噠嗪
6-Chloro-N,N-dimethylpyridazin-4-amine
N,N-二甲基-6-氯-4-氨基噠嗪
