克羅拉濱能抑制核苷酸還原酶，IC50為65 nM，還能抑制DNA聚合酶活性，是嘌呤核苷抗代謝產(chǎn)物。在至少兩種其他類型的治療已經(jīng)失敗后，這是FDA批準(zhǔn)的治療兒童復(fù)發(fā)或難治性急性淋巴細(xì)胞白血?。ˋLL)的藥物。
(2R,3S,4R,5R)-5-((Benzoyloxy)methyl)-3-fluorotetrahydrofuran-2,4-diyl dibenzoate
1,3,5-Tri-O-benzoyl-a-D-ribofuranose
(2S,3R,4R,5R)-2-Acetoxy-5-((benzoyloxy)methyl)tetrahydrofuran-3,4-diyl dibenzoate
(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate
(2R,3R,4S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
2,6-Dichloropurine
2-Chloro-7H-purin-6-amine
