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依托考昔能選擇性抑制COX-2,IC50為1.1μM(LPS誘導(dǎo)的前列腺素E2合成實(shí)驗(yàn)),而對(duì)COX-1的IC50則為116μM(凝血后血清血栓素B2生成實(shí)驗(yàn))。

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