阿法替尼是一種不可逆的 EGFR/HER2 雙重抑制劑，對 EGFRwt，EGFRL858R，EGFRL858R/T790M 都具有抑制作用，IC50 值分別為 0.5 nM，0.4 nM，10 nM 和 14 nM。阿法替尼是一種治療非小細(xì)胞肺癌（NSCLC）的藥物。它屬于酪氨酸激酶抑制劑家族的藥物。
2-(Diethoxyphosphoryl)acetic acid
(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
7-Chloro-4-hydroxyquinazoline
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
7-Fluoro-6-nitroquinazolin-4(3H)-one
(S)-Diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate
7-Chloro-6-nitroquinazolin-4(3H)-one
2,2-Diethoxy-N,N-dimethylethanamine
(E)-4-Bromobut-2-enoic acid
4-Hydroxy-3-nitrobenzonitrile
Methyl 3-amino-4-hydroxybenzoate
4-Chloro-7-fluoro-6-nitroquinazoline
(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
(S)-(+)-3-Hydroxytetrahydrofuran
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide dimaleate
N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)quinazolin-4-amine
(E)-4-(Dimethylamino)but-2-enoyl chloride
4,7-Dichloro-6-nitroquinazoline
2-Amino-4-fluoro-5-nitrobenzoic acid
