點(diǎn)擊化學(xué)指的是一類模塊化、高選擇性、條件溫和、高產(chǎn)率的偶聯(lián)反應(yīng)，以實(shí)現(xiàn)功能分子的高效快速合成。2022年諾貝爾化學(xué)獎(jiǎng)授予了生物正交反應(yīng)和點(diǎn)擊化學(xué)的開拓者，這兩個(gè)理念均秉持“大道至簡(jiǎn)”，即用簡(jiǎn)單高效的方法來(lái)實(shí)現(xiàn)分子的復(fù)合功能。點(diǎn)擊化學(xué)成功帶領(lǐng)化學(xué)進(jìn)入功能主義時(shí)代，推動(dòng)了材料化學(xué)、化學(xué)生物學(xué)、藥物化學(xué)和生物醫(yī)學(xué)等領(lǐng)域的發(fā)展。
3,6,9,12-Tetraoxapentadec-14-yn-1-ol
4,7,10,13,16-Pentaoxanonadeca-1,18-diyne
3,6,9,12-Tetraoxapentadec-14-yn-1-yl methanesulfonate
tert-Butyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
4,7,10,13,16-Pentaoxanonadec-18-yn-1-oic acid
3-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)prop-1-yne
tert-Butyl 4,7,10,13-tetraoxahexadec-15-yn-1-oate
tert-Butyl 3-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoate
2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoate
4,7,10,13-Tetraoxahexadeca-1,15-diyne
(E)-Cyclooct-4-enol
2,5-Dioxopyrrolidin-1-yl hex-5-ynoate
3-(2-(Prop-2-yn-1-yloxy)ethoxy)propanoic acid
N-(2-(2-(2-(2-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
(E)-Cyclooct-4-en-1-yl (2,5-dioxopyrrolidin-1-yl) carbonate
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine hydrochloride
tert-Butyl pent-4-ynoate
Oct-7-ynoic acid
2-(2-(2-Azidoethoxy)ethoxy)acetic acid
11-Azido-3,6,9-trioxaundecanol
2-(2-(2-Azidoethoxy)ethoxy)ethan-1-amine
14-Azido-3,6,9,12-tetraoxatetradecan-1-amine
Dbco-acid
Ethyl pent-4-ynoate
tert-Butyl (2-azidoethyl)carbamate
Triethylene Glycol Mono(2-propynyl) Ether
2-(2-Propynyloxy)ethylamine
5,6,11,12-Tetradehydrodibenzo[a,e]cyclooctene
17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
tert-Butyl 2-(2-(2-azidoethoxy)ethoxy)acetate
